You can even have minor problems with matching dies and shellholders. I bought RCBS dies and RCBS shellholder when I got my 22-250. A buddy gave me a partial box of factory ammunition he had left from when he had a 22-250 (he never reloaded). After firing it and some I loaded with new brass, the first reloading, sized with full contact between the die and shellholder, wouldn't quite chamber. Found out the shoulder wasn't getting pushed back enough. I ground a little bit off the top of the shellholder and the problem went away. I figure tolerance stacking between the chamber and sizing die was the culpret, since the factory ammunition chambered fine. Just luck of the draw that I had die at the big end of tolerance and a chamber at the small end.