I shoot 357 Maximum in an H&R HandiRifle with a 1:14 twist that was rechambered from 357 Mag with a fairly long throat.

Using the Lyman 35897 at an OAL of 2.350"

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I have used up to 21.0 grs of H4227 for about 1800 fps, and 21.0 grs of IMR4198 for 1550 fps. Further work will employ more IMR4198, probably up to a full or near full case.